Zarbee's Cough And Mucus With Zyrtec

There are no known interactions between the two products.


Can I give my 3yr old daughter (23 pounds) Zarbee's Cough and Mucus along with her Zyrtec?

Asked by Brooke On Apr 30, 2019

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Apr 30, 2019
Cough Syrup Bottle With Text Zarbees With Zyrtec.jpg


Zarbee's Cough and Mucus syrup is considered safe to take with Zyrtec (cetirizine), an antihistamine, as there is no known interaction between them.

When considering drug interactions, it is important to take note of all of the active ingredients in question.

For example, Zarbee's cough syrup contains multiple active ingredients, all of which need to be considered when looking for drug interactions.

Zarbee's Cough And Mucus

There are two Zarbee's Cough and Mucus products available, a children's version and a 'baby' version.[1]

The children's version contains the following ingredients:[2]

  • Dark honey
  • English Ivy Leaf Extract
  • Grapefruit Seed Extract
  • Vitamin C (ascorbic acid)
  • Zinc (zinc gluconate)

The baby version contains the following:[3]

  • Organic Agave Syrup
  • English Ivy Leaf Extract

The notable exclusion from the baby product is honey since most sources recommended against the use of honey in infants due to the risk of botulism.[4]

Zyrtec With Zarbee's

None of the ingredients used in Zarbee's Cough and Mucus are known to interact with Zyrtec.

In fact, all of the active ingredients in Zarbee's products have few known drug interactions.

English ivy has no known drug interactions and while grapefruit juice is notorious for its potential effects on many drugs, grapefruit seed extract isn't thought to have the same precautions (although it has been reported to affect the blood thinner warfarin).[5][6][7]

Additionally, taking Zyrtec and Zarbee's together isn't thought to increase the incidence of side effects for either.

Final Words

To answer your question specifically, there shouldn't be a problem giving your 3-year-old daughter Zyrtec and Zarbee's together. Using both may help to improve the symptoms your daughter is experiencing more than either alone.


There is no known interaction between Zyrtec (cetirizine) and Zarbee's Cough And Mucus products.

Video Summary

  1. ^ Zarbee's Manufacturer Website. Zarbee's
  2. ^ Zarbee's Children's Cough And Mucus Product Information. Zarbee's
  3. ^ Zarbee's Baby Cough And Mucus Product Information. Zarbee's
  4. ^ Infant botulism: advice on avoiding feeding honey to babies and other possible risk factors. PubMed
  5. ^ Therapeutic Research Center Natural Standard: English Ivy Monograph. Natural Standard (Subscription Required)
  6. ^ Therapeutic Research Center Natural Standard: Grapefruit Monograph. Natural Standard (Subscription Required)
  7. ^ Adverse effects by artificial grapefruit seed extract products in patients on warfarin therapy. PubMed

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