The dose you were prescribed, (500 mg) by mouth four times daily (i.e. every six hours), is within the dosage range of erythromycin for skin infections. The confined location of the bacterial infection, in this case your eyes, doesn't necessarily mean a lower dose is necessary. There are a variety of considerations your doctor is taking into account including:

  • Severity of the infection
  • Suspected species of bacteria causing the infection
  • Suspected susceptibility of the bacteria to erythromycin

Erythromycin Dosing Guidelines For Skin Infections

Below are the erythromcin dosing guidelines for skin infections:

Treatment Of Skin And Skin Structure Infections

  • Adults: 250 to 500 mg by mouth every 6 hours or 400 to 800 mg of erythromycin ethylsuccinate every 6 hours.
  • Infants, Children, and Adolescents: 30 to 50 mg/kg/day by mouth in 3 to 4 divided doses

Treatment Of Erythrasma Caused By Corynebacterium Minutissimum

Adults: 250 mg PO 3 times per day for 21 days.

Summary & Administration Recommendations

Your prescribed dose of erythromycin is well within the dosage guidelines for the medication. In regard to how to take erythromycin, it is well absorbed and can be taken without regard to food. However, it is often recommended to take the medication 1/2 hour before food or 2 hours after for optimal absorption.