Taking Oxycodone With Tamiflu

In our latest question and answer, the pharmacist discusses whether or not oxycodone can safely be taken with Tamiflu.

Feb 15, 2018

Sylray asked

If you take oxycodone, can you still take Tamiflu and Theraflu expressmax?

Answer

Oxycodone and Tamiflu may safely be taken together as there is no interaction between the two medications.

Taking Oxycodone With Tamiflu

Tamiflu (oseltamivir) is an oral anti-viral medication that is used both for the treatment of influenza and prophylaxis. Per the prescribing information for Tamiflu, it isn't expected to interact with many medications. It is not highly protein bound and its metabolism isn't greatly affected by the CYP liver enzymes

In fact, the only drug interaction that is listed for Tamiflu is with the medication probenacid. Administering Tamiflu with probenacid can result in a two-fold increase in Tamiflu concentration. However, as Tamiflu has a large window of safety, no dosage adjustments are needed.

Tamiflu has been tested with numerous medications that are often taken alongside of it. These drugs include:

  • Amoxicillin
  • Aspirin
  • Cimetidine
  • Antacids
  • Warfarin
  • Oxycodone

No drug interactions have been seen with Tamiflu and the above medications. Oxycodone is safe to take with Tamiflu and there is no drug interaction between the two.

Ready for a more personal experience with your meds?