Taking Mucinex DM With Tylenol Cold And Head Congestion

In our latest question and answer, the pharmacist discusses whether or not there is an interaction between Mucinex DM and Tylenol Cold And Head Congestion

Question

Can I take Mucimex DM, Benadryl, and Tylenol cold and head together?

Asked by Ashley On Apr 28, 2018

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On May 02, 2018

Mucinex DM should not be taken at the same time as Tylenol Cold And Head Congestion as they both contain guaifenesin. Taking both medications together is a therapeutic duplication and could potentially increase the risk of side effects.


Tylenol Cold And Head Congestion

Tylenol Cold And Head Congestion contains the following active ingredients:

  • Acetaminophen
  • Phenylephrine
  • Guaifenesin


Mucinex DM

Mucinex DM contains the following active ingredients:

  • Dextromethorphan
  • Guaifenesin


Taking Mucinex DM WIth Tylenol Cold And Head Congestion

Since both of these medications contain guafenesin, they should not be used together. It is important to always look at the labels of over the counter medications as they often contain more than one active ingredient.


If you are looking for cough relief, dextromethorphan is available as a single ingredient in products such as Delsym.

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Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of PharmacistAnswers.com. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Please feel free to reach out to him directly if you have any inquiries or want to connect! He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Brian.Staiger@PharmacistAnswers.com Office: 716-389-3076

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