Taking Buspar (Buspirone) Once A Day Versus Multiple Times Per Day

In our latest question and answer, the pharmacist discusses dosing recommendations for the anti-anxiety medication Buspar (buspirone).


I am taking 10mg of Buspar in the AM, as well as 20mg of Busbar and 10mg of Paxil in the PM. Can I take all these meds in the AM instead of splitting them up?

Asked by Chuck On Jun 16, 2018

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Jun 19, 2018

White Pills on tableYou should not combine your morning and evening dose of Buspar (buspirone). Buspar is indicated to be dosed two to three times a day and taking the entire dose at once in the morning will likely result in effects of the drug not lasting all day. It could also increase the risk of dose-dependent side effects, such as:

  • Dizziness
  • Drowsiness
  • Nervousness
  • Lightheadedness
  • Excitability
  • Anger/hostility
  • Confusion
  • Numbness
  • Headache
  • Incoordination

Buspar Dosing

Per the prescribing information for Buspar, it is indicated to be dosed as follows:

  • Starting dose of 7.5 mg by mouth twice daily, then increase as needed by 5 mg/day every 2 to 3 days. The usual maintenance dose is 15 to 30 mg/day administered in 2 to 3 divided doses

Effects of Buspar generally last 4-8 hours, but this can vary by individual. Increasing your dose in the morning will most likely not make it last longer, which is why the drug is recommended to take in divided doses throughout the day.

About the Pharmacist

Dr. Brian Staiger Pharm.D

Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of PharmacistAnswers.com. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Please feel free to reach out to him directly if you have any inquiries or want to connect! He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Brian.Staiger@PharmacistAnswers.com Office: 716-389-3076

About Buspar (Buspirone)

Buspar (Buspirone) is an anxiolytic (i.e. anti-anxiety) medication that is structurally and pharmacologically distinct from benzodiazepines, such as Valium and Xanax. Buspar does not impair psychomotor function, and does not cause physical dependence, an advantage over the use of benzodiazepines. Buspar also tends not to cause significant sedation. Buspar is not to be used for immediate effects, as consistent dosing of 2 weeks or longer is sometimes needed for onset of anxiolytic effects.

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