Taking Amoxicillin With Tamiflu

In our latest question and answer, the pharmacist discusses whether or not amoxicillin can be taken with Tamiflu.


Can you take Tamiflu and amoxicillin at the same time?

Asked by Sarah On Feb 16, 2018

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Feb 18, 2018

There are no drug interactions between Tamiflu (oseltamivir) and amoxicillin. Typically, an infection is caused by either bacteria or a virus, but may progress into multiple pathogens. As long as your physician is aware, or he/she prescribed both, it may be considered appropriate in some cases. We will discuss more information on Tamiflu and amoxicillin below.

Information About Tamiflu

Tamiflu is an antiviral that helps to treat seasonal influenza virus A or B (common flu). The important thing to note about Tamiflu is that it must be initiated as soon as possible once symptoms begin. The first 48 hours are the most critical time to make sure that Tamiflu is started. After 48 hours, the effect is much less, but can sometimes still be used in complicated cases. Tamiflu has been shown to reduce the duration of flu-like symptoms by about 24-32 hours assuming it is started early enough. Common side effects of Tamiflu include headache, nausea, vomiting, and diarrhea.

Because of the severe flu season this year, there have been reported shortages of Tamiflu in the community. This has especially affected the supply of liquid Tamiflu, commonly used for children. Many patients have had to call several pharmacies to ensure they have supply. Tamiflu suspension can be compounded by using the capsules in emergency situations, but is not recommended if the commercial product is available.

Information About Amoxicillin

Amoxicillin (Amoxil) is an aminopenicillin antibiotic that can treat a variety of infections including bronchitis, sinus infections, ear infections, skin infections, pneumonia and more. Amoxicillin is more stable to gastric acid as compared to penicillin. Additionally, it has coverage against more bacteria than penicillin. However, if you have a true penicillin allergy, you should not take any of the penicillins including amoxicillin. Azithromycin can cover several types of bacteria, but is not effective in treating the flu, the common cold, or other viral infections.

Like most antibiotics, amoxicillin may cause diarrhea, nausea, vomiting, and abdominal pain. Additionally, patients with seizure disorders must be careful taking penicillins, as this class has been associated with increasing the risk of seizures. Drug interactions can also be a concern so always check each new medication prior to starting a new therapy.

About the Pharmacist

Dr. Kevin Davis Pharm.D

Dr. Kevin Davis is a licensed pharmacist with experience in retail and hospital pharmacy. He graduated from the University of Florida with a Doctor of Pharmacy degree in 2015 and a Master of Healthcare Administration degree from Adventist University in 2017. He is also a Board Certified Pharmacotherapy Specialist since 2016.

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