Taking Advil With Coricidin Chest and Cough

There is no interaction between Advil and Coricidin Chest and Cough. There are other considerations however. The pharmacist discusses this and more in our latest question and answer.


Can I take Advil with Coricidin HBP Chest and Cough medicine?

Asked by Janice On Dec 06, 2018

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Dec 06, 2018

Advil With Coricidin Chest And Cough

Advil (ibuprofen) is safe to take with Coricidin Chest And Cough, which contains two active ingredients:

  • Dextromethorphan
  • Guaifenesin

Dextromethorphan is a cough suppressant while guaifenesin is an expectorant, which helps to thin and loosen mucus secretions. Both have no interaction with Advil and are safe to take with it.

It is important to note that Advil can raise blood pressure, especially with long term use. As you are presumably taking Coricidin since it is safe in those with high blood pressure, be sure to take into consideration how Advil could affect it.

In general, it is recommended to monitor blood pressure when starting therapy with a NSAID (non-steroidal anti-inflammatory drug), like ibuprofen.

One study found that NSAIDs can increase blood pressure in individuals with or without diagnosed hypertension, with the greatest increases in those on antihypertensive therapy. It concluded:

Patients at risk for hypertension should be monitored for changes in blood pressure during NSAID treatment.

Additionally, many studies report that those taking certain blood pressure medications may be more affected than others. For example, NSAIDs, like Advil can antagonize the effects of some ACE-Inhibitors (e.g. lisinopril). Also, taking a NSAID with diuretics can increase the risk of acute kidney disease.

So, while Advil is safe with Coricidin Chest And Cough, it may not be recommended by your doctor if you have high blood pressure or are on blood pressure medication.

Alternative analgesics, such as acetaminophen, may be a better option for you. Be sure to speak with your doctor regarding whether or not Advil is safe in your particular medical situation.


There is no drug interaction between Advil and Coricidin Chest And Cough (Dextromethorphan; Guaifenesin). However, NSAIDs like Advil can raise blood pressure and may interact with blood pressure medication.

About the Pharmacist

Dr. Brian Staiger Pharm.D

Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of PharmacistAnswers.com. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Please feel free to reach out to him directly if you have any inquiries or want to connect! He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Brian.Staiger@PharmacistAnswers.com Office: 716-389-3076

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