Is Lunesta 1mg Strong Enough To Work For Sleep?

In our latest question and answer, the pharmacist discusses whether or not Lunesta 1mg is strong enough to be effective in treating insomnia.


Is 1mg of Lunesta enough to sleep?

Asked by GUNNER On Apr 23, 2018

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Apr 23, 2018

Lunesta (eszopiclone) is a sedative hypnotic medication indicated for the treatment of insomnia. Lunesta has some similar properties to other sedative hypnotic medication such as benzodiazepines but has advantages over these when it comes to sleep induction.

Lunesta is much less likely to cause a next day hangover effect or cognitive/motor function impairment like some other hypnotics. This is due to the fact that the primary metabolites of Lunesta are not active so the active effects of the medication do not linger in your system. 

Lunesta should be given immediately before sleep as its onset of action is very fast. Lunesta should be given at a starting dose of 1 mg, taken with at least seven to eight hours of time before planned time of awakening. The dose may be titrated (i.e. increased) up to 2mg to 3mg nightly, but these doses increase the risk of side effects. The lowest possible effective dose of Lunesta should be utilized. Lunesta should be given with a full glass of water on an empty stomach as food can decrease the rate of onset as well as overall effect of the medication. 

Common drugs that can interact with Lunesta include but are not limited to:

  • Melatonin
  • St. Johns Wort
  • Anti-fungal medication (ketoconazole, fluconazole)
  • Lorazepam
  • Olanzapine

Common side effects you may experience while taking Lunesta include but are not limited to:

  • Depressed mood
  • Sleep walking
  • Motor or cognitive impairment
  • Hallucinations
  • Headache
  • Dizziness/daytime "hangover" effect

You should let your doctor know about any side effects you may be experiencing while taking Lunesta. 

About the Pharmacist

Dr. Adam DeRue Pharm.D

Dr. Adam DeRue is a Doctor Of Pharmacy and registered pharmacist. He graduated from the Albany College of Pharmacy in 2008.

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