Jan asked
When do concentrations of Admelog peak?
At a glance
- Admelog is a 'follow-on' brand to Humalog, both of which contain insulin lispro. They begin working about 10-15 after administration, peak around 30-90 minutes after administration, and last 3 to 5 hours.
Answer
Admelog (insulin lispro) is a rapid-acting insulin product used to control blood glucose.
It begins to work 15-30 minutes after injecting under the skin (subcutaneously) and has a duration of action around 3 to 5 hours.[1]
Peak concentrations are reached anywhere between 30 and 90 minutes after injecting, which is faster when compared to regular insulin products (60 to 90 minutes).[2]
What Is Admelog?
As mentioned above, Admelog is a rapid-acting insulin, known as insulin lispro.
It is actually the same type of insulin as Humalog (insulin lispro), another rapid-acting insulin, but isn't technically a generic of it.
The FDA classifies Admelog as a "follow-on" drug brand product, which are approved by the FDA based on the safety and effectiveness of the original brand they are ''following".
This allows for a faster approval process than normal, with the ultimate goal being to increase competition in the marketplace, ideally resulting in lower prices for consumers.[3]
At the time of Admelog's FDA approval in December of 2017, FDA commissioner Scott Gottlieb stated the following regarding:[4]
“One of my key policy efforts is increasing competition in the market for prescription drugs and helping facilitate the entry of lower-cost alternatives. This is particularly important for drugs like insulin that are taken by millions of Americans every day for a patient’s lifetime to manage a chronic disease,”
References
- ^ Elsevier ClinicalKey: Admelog Monograph. ClinicalKey
- ^ Admelog Prescribing Information. AccessFDA
- ^ 505 (b)(2) Regulatory Pathway for New Drug Approvals. Pharmacy Times
- ^ FDA approves Admelog, the first short-acting "follow-on" insulin product to treat diabetesPharmacy Times
