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Overview What is admelog Summary

How Long Does It Take For Admelog To Reach Peak Concentrations?

In our latest question and answer, the pharmacist discusses how long it takes for Admelog to reach peak concentrations.

Question

When do concentrations of Admelog peak?

Asked by Jan On Apr 14, 2019

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Apr 17, 2019
Vector Image Illustration Of Insulin

Overview

Admelog (insulin lispro) is a rapid-acting insulin product used to control blood glucose.

It begins to work 15-30 minutes after injecting under the skin (subcutaneously) and has a duration of action around 3 to 5 hours.[1]

Peak concentrations are reached anywhere between 30 and 90 minutes after injecting, which is faster when compared to regular insulin products (60 to 90 minutes).[2]


What Is Admelog?

As mentioned above, Admelog is a rapid-acting insulin, known as insulin lispro.

It is actually the same type of insulin as Humalog (insulin lispro), another rapid-acting insulin, but isn't technically a generic of it.

The FDA classifies Admelog as a "follow-on" drug brand product, which are approved by the FDA based on the safety and effectiveness of the original brand they are ''following".

This allows for a faster approval process than normal, with the ultimate goal being to increase competition in the marketplace, ideally resulting in lower prices for consumers.[3]

At the time of Admelog's FDA approval in December of 2017, FDA commissioner Scott Gottlieb stated the following regarding:[4]

“One of my key policy efforts is increasing competition in the market for prescription drugs and helping facilitate the entry of lower-cost alternatives. This is particularly important for drugs like insulin that are taken by millions of Americans every day for a patient’s lifetime to manage a chronic disease,”

Summary

Admelog is a 'follow-on' brand to Humalog, both of which contain insulin lispro. They begin working about 10-15 after administration, peak around 30-90 minutes after administration, and last 3 to 5 hours.

References
  1. ^ Elsevier ClinicalKey: Admelog Monograph. ClinicalKey
  2. ^ Admelog Prescribing Information. AccessFDA
  3. ^ 505 (b)(2) Regulatory Pathway for New Drug Approvals. Pharmacy Times
  4. ^ FDA approves Admelog, the first short-acting "follow-on" insulin product to treat diabetesPharmacy Times

About the Pharmacist

Dr. Brian Staiger Pharm.D

Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of PharmacistAnswers.com. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Please feel free to reach out to him directly if you have any inquiries or want to connect! He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Brian.Staiger@PharmacistAnswers.com Office: 716-389-3076

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