How Long Does Amoxicillin Last In The Fridge?

In our latest question and answer, the pharmacist discusses how amoxicillin suspension should be stored and how long it lasts for.


I was just dispensed amoxicillin and the section of the label that says how long it is good in the fridge is cut off. How long is it good in the refrigerator after getting from the pharmacy?

Asked by Jeremy On Jul 19, 2018

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Jul 19, 2018

Amoxicillin liquids (i.e. suspensions) can actually be stored in the refrigerator or at room temperature, however refrigeration is preferable as it increases tolerability for most individuals, especially children. In other words, it tastes better chilled. Regardless of how you store amoxicillin suspension, they all expire after 14 days

Amoxicillin suspension is made by a variety of generic manufacturers (e.g. Sandoz, Teva, Par, Dr. Reddy) but all have directions similar to the following (which is from the prescribing information for brand Amoxil suspension):

"Keep bottle tightly closed. Any unused portion of the reconstituted suspension must be discarded after 14 days. Refrigeration preferable, but not required."

The above required storage conditions are the same for all strengths of amoxicillin suspension from all manufacturers, which include:

  • Amoxicillin 125mg/5mL
  • Amoxicillin 200mg/5mL
  • Amoxicillin 250mg/5mL
  • Amoxicillin 400mg/5mL

Be sure to always shake amoxicillin suspension well prior to each administration and measure each dosage with calibrated spoon, cup, or oral syringe to ensure accuracy. The measured dose of suspension may be added to formula, milk, fruit juice, water, ginger ale, or cold drinks for ease of administration.

After picking up amoxicillin from the pharmacy (the pharmacist will reconstitute a dry powder by adding water to it), store it under refrigeration (preferred) or at controlled room temperature for up to 14 days and discard any unused portion after 14 days.

About the Pharmacist

Dr. Brian Staiger Pharm.D

Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Please feel free to reach out to him directly if you have any inquiries or want to connect! He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Office: 716-389-3076

About Amoxicillin

Amoxicillin is an semisynthetic "aminopenicillin" similar to ampicillin and penicillin. It does however, have a broader spectrum of antibacterial effects than penicillin and is better absorbed than ampicillin. Amoxicillin is used to treat a variety of infections including: Otitis media, bronchitis, sinusitis, and bacterial cystitis. In general, amoxicillin can be given with or without food but food may reduce any gastrointestinal side effects.

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