Angina (chest pain) can be caused by a variety of factors but typically arises due to a lack of blood flow to the heart. Fluconazole, an antifungal medication, is generally recommended to be used with caution in those with pre-existing cardiac problems.

Fluconazole Cardiac Precautions

Fluconazole is classified as an "azole" antifungal medication, which are associated with certain types of arrhythmias, most commonly QT prolongation. Although rare, QT prolongation and torsade de pointes (a specific abnormal heart rhythm) have been reported with fluconazole use, especially when it is combined with other medications that potentially affect heart rhythm.

Most reports of arrhythmia with fluconazole use in those taking very high doses, patients with multiple risk factors and pre-existing structural cardiac disease. Most of the data available points to it being extremely unlikely that usual therapeutic dosages of fluconazole could to cause abnormal heart rhythm on its own with no pre-existing conditions.

In your case, angina is a fairly broad symptom that could the result of a variety of issues. Caution would be recommenced in regard to fluconazole use in your situation until you know the cause of angina and if the medication is prescribed, monitoring is advised.