The shingles (i.e. herpes zoster) vaccine Shingrix does not contain neomycin. This is good news for those with a neomycin allergy as the other shingles vaccine, Zostavax, contains neomycin.


As Shingrix does not contain neomycin, it may be administered to those with a neomycin allergy.


Shingrix Ingredients

Each 0.5 ml dose of Shingrix contains the following ingredients:

  • Recombinant gE antigen (50 mcg)
  • Monophosphoryl lipid A (50 mcg)
  • QS-21 50 mcg (saponin purified from plant extract Quillaja saponaria)
  • Sucrose 20 mg
  • Sodium chloride 4.385 mg
  • DOPC (dioleoyl phosphatidylcholine) 1 mg 
  • Potassium dihydrogen phosphate 0.54 mg
  • Cholesterol 0.25 mg 
  • Sodium dihydrogen 0.160 mg 
  • Phosphate dihydrate
  • Disodium phosphate anhydrous 0.15 mg 
  • Dipotassium phosphate 0.116 mg 
  • Polysorbate 80 0.08 mg 
  • Residual amounts of host cell proteins (≤3.0%) and DNA (≤2.1 picograms) from the manufacturing process.


In addition, the the vial stoppers are not made with natural rubber latex.


Summary

  • Shingrix does not contain neomycin and may be administered to those with a neomycin allergy.