Flagyl (metronidazole) is an anti-bacterial and anti-protozoal agent used for the treatment of many different indications including pneumonia, respiratory infections, intra-abdominal infections and bacterial vaginosis. While typically well tolerated, it is associated with a various side effects, one of which is sexual dysfunction and libido decrease.


Metronidazole - Sexual Dysfunction

The incidence of sexual side effects isn't great, but have nevertheless been reported. Reported side effected include:

  • Libido decrease
  • Dyspareunia (painful intercourse)
  • Vaginitis
  • Delayed ejaculation
  • Anorgasmia (absence of orgasm)


The incidence rate appears to be between 1% and 5% for the above adverse effects. If you do experience any side effects on metronidazole, they should resolve within a few days. Metronidazole has a half life of about 8 hours and should be completely eliminated from the body in 2 to 3 days.