No, Butrans (buprenorphine) patches do not have 'sulfa' containing components and may be safely used in those with 'sulfa' allergies.


Butrans Ingredients

Butrans contains the following ingredients:

  • Buprenorphine
  • Levulinic acid
  • Oleyl oleate
  • Povidone
  • Polyacrylate cross-linked with aluminum


Below, is the chemical structure of buprenorphine:

Buprenorphine Chemical Structure

As you can see, there are no sulfa structures contained in buprenorphine. It is considered safe to use in those with known allergies or sensitivities to sulfa containing drugs.

Dr. Brian Staiger Pharm.D
Dr. Brian Staiger Pharm.D

Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of PharmacistAnswers.com. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Please feel free to reach out to him directly if you have any inquiries or want to connect! He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Brian.Staiger@PharmacistAnswers.com Office: 716-389-3076