No, Butrans (buprenorphine) patches do not have 'sulfa' containing components and may be safely used in those with 'sulfa' allergies.


Butrans Ingredients

Butrans contains the following ingredients:

  • Buprenorphine
  • Levulinic acid
  • Oleyl oleate
  • Povidone
  • Polyacrylate cross-linked with aluminum


Below, is the chemical structure of buprenorphine:

Buprenorphine Chemical Structure

As you can see, there are no sulfa structures contained in buprenorphine. It is considered safe to use in those with known allergies or sensitivities to sulfa containing drugs.