Can You Take Tylenol With Tamiflu?

In our latest question and answer, the pharmacist discusses whether or not you can take Tylenol (acetaminophen) with Tamiflu.


Can you take Tylenol with Tamiflu?

Asked by Melissa On Feb 06, 2018

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Feb 06, 2018

Tylenol (acetaminophen) and Tamiflu (oseltamivir) are safe to take together. There is no listed interaction between the two drugs and there have been no reports of adverse effects when combining the two. 

In fact, the prescribing information for Tamiflu specifically states that the following medications are safe to use in combination with the antiviral:

  • Amoxicillin
  • Acetaminophen
  • Aspirin
  • Cimetidine
  • Antacids (magnesium and aluminum hydroxides and calcium carbonates)

Tamiflu has very few reported drug interactions and is safe to use with most medications. One of the only listed drug interactions is with probenecid, a agent used for the treatment of gout.

As flu symptoms tend to involve fever and muscle aches, Tylenol (acetaminophen) is a good choice to use in conjunction with Tamiflu to appropriately manage symptoms while treating the infection.

About the Pharmacist

Dr. Brian Staiger Pharm.D

Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Please feel free to reach out to him directly if you have any inquiries or want to connect! He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Office: 716-389-3076

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