Momof3 asked
Can you take phentermine in morning and NyQuil at night?
Answer
Phentermine (brand name Adipex-P) and NyQuil may be used together as there is no listed or reported interaction between the two. However, using both together could lessen the effect of both medications as discussed below.
Phentermine - NyQuil Information
NyQuil is a combination ingredient cough/cold product and contains the following ingredients:
- Acetaminophen (analgesic)
- Dextromethorphan (cough suppressant)
- Doxylamine (sedating antihistamine)
Phentermine is a sympathomimetic medication, chemically similar to amphetamines and is used for the treatment of obesity.
While there is no interaction between NyQuil and phentermine, they do have conflicting effects. Phentermine can have amphetamine-like effects and is a CNS (central nervous system) stimulant. These effects include:
- Increased concentration
- Increased attentiveness
- Restlessness
- Over-stimulation
NyQuil contains doxylamine, a sedating antihistamine. Although there is no drug-drug interaction, the sedatory effects of NyQuil may be decreased due to the stimulant action of phentermine. Similarly, the stimulatory effects of phentermine may be decreased if used with NyQuil.
If you are looking to avoid the conflicting effects of both medications, try to space them as far apart as possible. The duration of action of phentermine varies, but can last anywhere from 12-16 hours. The effects of NyQuil generally last around 4 to 6 hours.
