Can You Take Amoxicillin And DayQuil Together?

There is no interaction between amoxicillin and DayQuil. They can be used together safely.

Question

I just got prescribed amoxicillin for a respiratory infection. I wanted to know if it was okay to use DayQuil with it?

Asked by Cher On Dec 06, 2018

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Dec 06, 2018

Taking Amoxicillin With DayQuil

The antibiotic amoxicillin is safe to take with DayQuil. There is no interaction between them.


DayQuil is a combination ingredient cough/cold/flu product which contains three medications (DayQuil Severe has four):

  • Acetaminophen
  • Dextromethorphan
  • Phenylephrine
  • Guaifenesin (DayQuil Severe only)


Acetaminophen is the active ingredient in Tylenol as well. It is an analgesic and anti-pyretic.


Dextromethorphan is a cough suppressant, using for treating chronic, nonproductive coughs.


Phenylephrine is a nasal decongestant, similar to pseudoephedrine but is available over the counter (pseudoephedrine is also available without a prescription but must be in a locked case or behind the pharmacy counter).


Guaifenesin is an expectorant, which helps to loosen and thin bronchial secretions.


All of the ingredients in DayQuil (and DayQuil Severe) do not interact with amoxicillin. You can feel safe taking them together.


In fact, amoxicillin is safe with the vast majority of over the counter cough/cold and flu medications.


There is a very minor interaction with aspirin, as they both compete for protein binding sites. Using both has the risk of increasing the side effects of either drug. Nevertheless, even though an interaction is possible, they are often used together.


Summary

There is no drug interaction between DayQuil and amoxicillin. They can safely be used together.

About Amoxicillin

Amoxicillin is a semisynthetic "aminopenicillin" similar to ampicillin and penicillin. However, it has a broader spectrum of activity effects than penicillin and is better absorbed than ampicillin (which allows it to be dosed less frequently).

Amoxicillin is used to treat a variety of infections including:

  • Otitis media (ear infections)
  • Bronchitis
  • Sinusitis (sinus infection)

Amoxicillin can be taken with or without food. Food may reduce the risk of gastrointestinal side effects.

Amoxicillin is available in a variety of dosage forms, including:

  • Tablets
  • Capsules
  • Suspension
  • Extended release tablets (Moxatag)

About the Pharmacist

Dr. Brian Staiger Pharm.D

Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of PharmacistAnswers.com. He graduated from the University At Buffalo with a Doctor Of Pharmacy degree in 2010. He has been featured in several publications including the Huffington Post as well as a variety of health and pharmacy related blogs. Please feel free to reach out to him directly if you have any questions or want to connect! [email protected]; Office: 716-389-3076

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