Can You Store Shingrix In The Freezer?

In our latest question and answer, the pharmacist discusses whether or not the shingles vaccine Shingrix can be stored in the freezer.

Question

I accidentally stored the Shingrix vaccine in the freezer, does it affect it effectiveness?

Asked by Sheila On Dec 20, 2017

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Dec 21, 2017

According to the manufacturer of Shingrix, GlaxoSmithKline, Shingrix should NOT be stored in the freezer. If any component of the vaccine has been frozen, it must be discarded and is not to be used for administration.


 Shingrix is supplied as two components:

  • A single-dose vial of lyophilized gE antigen component (this vial has a brown cap)
  • A single-dose vial of adjuvant suspension component (this vial has a blue-green cap)


If either component of the vaccine is frozen, it should be discarded.


Per the package insert of Shingrix:

Storage before Reconstitution

  • Adjuvant suspension component vials: Store refrigerated between 2 degrees Celsius and 8 degrees Celsius  (36 degrees Fahrenheit and 46 degrees Fahrenheit). Protect vials from light. Do not freeze. Discard if the adjuvant suspension has been frozen.
  • Lyophilized gE antigen component vials: Store refrigerated between 2 degrees Celsius and 8 degrees Celsius  (36 degrees Fahrenheit and 46 degrees Fahrenheit). Protect vials from light. Do not freeze. Discard if the antigen component has been frozen.


Storage after Reconstitution

After reconstitution, administer SHINGRIX immediately or store refrigerated between 2 degrees Celsius and 8 degrees Celsius  (36 degrees Fahrenheit and 46 degrees Fahrenheit) and use within 6 hours. Discard reconstituted vaccine if not used within 6 hours. Do not freeze. Discard if the vaccine has been frozen.

About the Pharmacist

Dr. Brian Staiger Pharm.D

Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of PharmacistAnswers.com. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Please feel free to reach out to him directly if you have any inquiries or want to connect! He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Brian.Staiger@PharmacistAnswers.com Office: 716-389-3076

Recent Questions