Can You Open Strattera Capsules?

In our latest question and answer, the pharmacist discusses whether or not Strattera capsules can be opened.


My 8 year old is on Strattera. He can not swallow the pill. The doctor said there is nothing else she can prescribe? It says they cannot be open. Are their any alternatives to the form of medication?

Asked by Renee On Mar 21, 2018

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Mar 22, 2018

Strattera (Atomoxetine) capsules should not be opened according to the manufacturer. Per the prescribing information:

"Do not chew, crush, or open the capsules. Swallow STRATTERA capsules whole with water or other liquids. Tell your doctor if you or your child cannot swallow STRATTERA whole. A different medicine may need to be prescribed.

Avoid touching a broken STRATTERA capsule. Wash hands and surfaces that touched an open STRATTERA capsule. If any of the powder gets in your eyes or your child’s eyes, rinse them with water right away and call your doctor."

The above information applies for all generic Strattera (Atomoxetine) products as well.

The reason that you should not open Strattera capsules is that the powder is a known ocular irritant. Opening the capsules could, and most likely will, cause the powder to become airborne and can cause extreme discomfort if it gets into the eyes. The powder is easily transferred from the hands to the eye area as well.

In addition, there have been anecdotal reports that the powder from Strattera capsules can be irritating to the esophagus and stomach, although this hasn't been confirmed.

If you are looking for alternative ways to take Strattera, it may be worth locating a compounding pharmacy, which may be able to provide the drug in a dosage form that is better tolerated such as a suspension.

If you are looking for alternative ADHD medications, that are many options.

Non-Stimulant Strattera Alternatives

Strattera is considered a non-stimulant medication has a unique mechanism of action. It is thought to work primarily by increasing the amount of the neurotransmitter norepinephrine. It is a popular non-amphetamine options for the treatment of ADHD.

If you are looking for other non-stimulant (i.e. non-amphetamine), below are some possible options:

  • Kapvay (Clonidine extended release)
  • Intuniv (Guanfacine extended release)

Both of the above medications are similar and worth discussing with the doctor.

About the Pharmacist

Dr. Brian Staiger Pharm.D

Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Please feel free to reach out to him directly if you have any inquiries or want to connect! He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Office: 716-389-3076

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