Humira can be given around the same time you receive steroid injections. However, it is important to note that most "drug-interaction checkers" will note a moderate interaction between the two since they both suppress the immune system, which can increase your risk of infection.


Humira With Steroids

In general, it is important to be closely monitored for the development of signs and symptoms of infection if Humira is co-administered with a corticosteroid. Humira increases the risk for serious infections, that may lead to hospitalization. Individuals using concomitant immunosuppressants (including corticosteroids) may be at greater risk of infection.


Corticosteroids include:

  • Cortisone
  • Budesonide
  • Fludrocortisone
  • Flunisolide
  • Methylprednisolone
  • Prednisone
  • Prednisolone
  • Triamcinolone


The interaction with Humira includes injectable and oral steroids. The use of both is not a contraindication, but caution is advised. It is important to let your doctors know all of the medications you are taking.