Are Yaz And Loryna The Same Birth Control?

In our latest question and answer, the pharmacist discusses why Yaz and Loryna are "the same" and can be interchanged.

Are Yaz And Loryna The Same Birth Control?
May 06, 2018

Evelyn asked

Is Yaz and Loryna the same birth control?

Answer

Yaz LorynaYaz and Loryna contain the same dose of active ingredients (ethinyl estradiol 0.02mg and drospirenone 3mgto help prevent pregnancy. They are both also indicted to treat acne vulgaris and premenstrual dysphoric disorder (PMDD). Yaz and Loryna can be switched between one another and other brand names containing the same active ingredients (e.g. Gianvi, Vestura).

Some pharmacies will switch to carrying different brand names of birth control pills and will switch between them depending on what they have in stock. This is fine as long as they have the same amount of active ingredients, are considered bioequivalent, and the doctor does not specify they cannot be switched.

It is important to note that while the active ingredients are the same for both Yaz and Loryna, they do have different inactive ingredients, which is why the tablets look different.

Below are the ingredients for both Yaz and Loryna.

Yaz Ingredients

The 24 active, hormone pills contain: 

  • Drospirenone 3 mg
  • Ethinyl Estradiol 0.02 mg
  • Corn Starch
  • Ferric Oxide
  • Hypromellose
  • Lactose
  • Magnesium Stearate
  • Talc
  • Titanium Dioxide

The 4 inactive, placebo pills contain:

  • Corn Starch
  • Hypromellose
  • Lactose
  • Magnesium Stearate
  • Povidone
  • Talc
  • Titanium Dioxide
Loryna Ingredients

The 24 active, hormone pills contain: 

  • Drospirenone 3mg
  • Ethinyl Estradiol 0.02mg
  • Croscarmellose Sodium
  • Ferric Oxide
  • Lactose
  • Magnesium Stearate
  • Polyethylene Glycol
  • Polysorbate 80
  • Polyvinyl Alcohol
  • Povidone K30
  • Pregelatinized Starch
  • Talc
  • Titanium Dioxide

The 4 inactive, placebo pills contain:

  • Croscarmellose Sodium
  • Lactose
  • Magnesium Stearate
  • Polyethylene Glycol
  • Polysorbate 80
  • Polyvinyl Alcohol
  • Povidone K30
  • Pregelatinized Starch
  • Talc
  • Titanium Dioxide

Information About Ethinyl Estradiol / Drospirenone

The two hormones ethinyl estradiol and drospirenone are contained in these combination pills and are used to prevent pregnancy. They are also indicted for the treatment of acne and PMDD. These pills do not prevent sexually transmitted infections (STIs).

How It Works

Birth control pills mostly work by preventing ovulation by maintaining steady hormone levels in the body. However, other changes to the cervical mucus a lining of the uterus can also help. Changes in cervical mucus can make it difficult for sperm to enter the uterus, and a change in the lining of the uterus would reduce the change of implantation.

Drospirenone is a unique progestin and is considered a "fourth generation" progestin. It is similar to spironolactone and has both antimineralocorticoid and antiandrogenic properties. In addition to contraceptive use, drospirenone can reduce acne as well as alleviate premenstrual complaints, such as:

  • Negative mood
  • Water retention
  • Increased appetite

Both Yaz and Loryna also contain 24 active pills, as opposed to the more commonly seen 21 active pill regimens. The extra 3 days of active pills are thought to help reduce premenstrual symptoms.

Contraindications

Birth control should not be used in women who have:

  • Blood clotting disorders or history of blood clots
  • Coronary artery disease
  • Cerebral vascular disease
  • Known or suspected breast or uterine cancer
  • Undiagnosed abnormal genital bleeding Liver disease, liver cancer, jaundice, or previous jaundice with pill use Known or suspected pregnancy
Warnings

Smoking while taking birth control pills can increase the risk of having cardiovascular side effects (heart attack, stroke, blood clot). Smoking should be avoided. This risk increases with heavy smoking and with age. The risk is significantly higher in women over the age of 35 years.

Potential Side Effects
  • Nausea
  • Cramping
  • Bloating
  • Vomiting
  • Weight gain
  • Breast tenderness
  • Headache
  • Spotting

Other Information

  • Consult your doctor when starting any new medications, over-the-counter medications, or supplements.
  • Birth control pills may interact with: rifampin, anticonvulsants (phenobarbital, phenytoin, carbamazepine), and some antibiotics (penicillins, tetracycline, griseofulvin).
  • If you suspect you might be pregnant, consult a doctor immediately, as this medication may be harmful to a fetus.
  • Consult your doctor immediately if you notice symptoms of an allergic reaction, breast discharge or lumps, pain or swelling or unusual redness in your lower legs, chest pain or tightness, numbness or weakness in arms or legs or on one side of the body, dark urine or pale stool, or yellowing of the skin or eye.

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