Amoxicillin With High Blood Pressure Medication

In our latest question and answer, the pharmacist discusses whether or not it is safe to take amoxicillin if you are taking medication for high blood pressure.

Question

I have a tooth infection. My dentist told me to take amoxicillin three times per day; however I’m on high blood pressure pills as well. Is it okay to take these together? Is there any side effects? Thanks

Asked by Gina On Jul 31, 2018

Answered by
Medical Content Reviewed By PharmacistAnswers Staff

On Aug 02, 2018

There are no interactions between Amoxicillin and high blood pressure medications. It is considered safe to take both types of medication together. Amoxicillin is also not known to cause any increases in blood pressure so should be safe in those who have been diagnosed with it.


 Amoxicillin is typically a well tolerated drug with the following possible side effects:

  • Candidiasis infections (yeast infections)
  • Hypersensitivity reactions including rashes, urticaria (hives), Stevens-Johnson syndrome and anaphylaxis 
  • Nausea, vomiting or diarrhea
  • Black hairy tongue
  • Anemia
  • Dizziness
  • Anxiety
  • Insomnia
  • Confusion
  • Behavioral changes


If side effects are experienced, most patients will complain of the gastrointestinal side effects of nausea, vomiting or diarrhea.


As with any antibiotic, it is important to take the medication exactly as prescribed and to finish the full course of therapy. If taking an antibiotic to treat an infection, this means that patients should not stop the antibiotic when they start to feel better. The World Health Organization (WHO) recommends finishing all antibiotics as directed by your doctor. This helps in the prevention of the bacteria developing resistance to the antibiotics that are being prescribed.


There is emerging evidence that antibiotic treatment length may be able to be shortened, meaning patients may not need to take some treatments for as long of a time. However, this is new information and more studies will need to be done before changes in recommended treatment lengths are changed.  

About the Pharmacist

Ms. Jennifer Hauder RPh

Jennifer Hauder is a registered pharmacist in the state of Illinois. She has over 10 years experience as a pharmacist in the retail and pharmacy benefit managers (PBM) settings. She became a pharmacist due to her interest in healthcare and the opportunity to help others with their healthcare needs. When not working, she enjoys spending time with her husband, three children and two black labs Lucky and Charms.

About Amoxicillin

Amoxicillin is an semisynthetic "aminopenicillin" similar to ampicillin and penicillin. It does however, have a broader spectrum of antibacterial effects than penicillin and is better absorbed than ampicillin. Amoxicillin is used to treat a variety of infections including: Otitis media, bronchitis, sinusitis, and bacterial cystitis. In general, amoxicillin can be given with or without food but food may reduce any gastrointestinal side effects.

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