Advil Sinus Congestion & Pain With Protontix Interaction

Advil Sinus Congestion and Pain is safe to take with Protontix (pantoprazole).

Nov 28, 2018

Mel asked

Hi! Can I take Advil Sinus Congestion and Pain with Pantoprazole? Thank you.

At a glance

  • There is no drug interaction between Advil Sinus Congestion & Pain and Protonix (pantoprazole).

Answer

Yes, Advil Sinus Congestion & Pain and Protonix (pantoprazole) may safely be taken together as there is no drug interaction between them.

Advil Sinus Congestion & Pain is a combination ingredient product, which contains the following active ingredients:

  • Ibuprofen 200mg (NSAID)
  • Phenylephrine HCI 10 mg

Both active ingredients are safe with Protonix.

It is important to note for maximum effectiveness, most sources (including the Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease) recommend to take proton pump inhibitors like Protonix (pantoprazole) on an empty stomach, 30-60 minutes before meals or other medication.

So, while you can take Advil Sinus Congestion & Pain and Protonix (pantoprazole) at the same time, you may want to consider taking Protonix first thing in the morning, by itself, for best effects.

Lastly, taking Advil Sinus Congestion & Pain intermittently and at the recommended doses is likely to be safe and effective. However, long term use of NSAIDs (like ibuprofen) has been linked to an increased risk of stomach bleeds and ulcers.

Proton pump inhibitors like Protonix can actually decrease the risk of these NSAID induced bleeding events.

In fact, the American Geriatric Society recommends the use of proton pump inhibitors in elderly individuals on long term NSAID therapy to provide gastro-protection.

References
  1. Guidelines for the diagnosis and management of gastroesophageal reflux disease. PubMed
  2. The use of proton pump inhibitors in treating and preventing NSAID-induced mucosal damage. PubMed
  3. A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly. PubMed

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