Accidentally Took Two Doses Of Dexilant

The pharmacist discusses potential adverse effects of accidentally taking an extra dose of Dexilant (dexlansoprazole).

Jul 06, 2018

Amos asked

I took two Dexilant pills in the same day by mistake. Am I in danger?

Answer

Accidentally taking two doses of Dexilant most likely will not cause any serious adverse events. The following is from the prescribing information for Dexilant:

There have been no reports of significant overdose of DEXILANT. Multiple doses of DEXILANT 120 mg and a single dose of DEXILANT 300 mg did not result in death or other severe adverse events. However, serious adverse events of hypertension have been reported in association with twice daily doses of DEXILANT 60 mg. Non-serious adverse reactions observed with twice daily doses of DEXILANT 60 mg include hot flashes, contusion, oropharyngeal pain, and weight loss. Dexlansoprazole is not expected to be removed from the circulation by hemodialysis. If an overdose occurs, treatment should be symptomatic and supportive.

Most likely, you may just having an increased incidence of the more common side effects of Dexilant, which include:

  • Abdominal Pain
  • Nausea
  • Vomiting
  • Flatulence

The side effect of hypertension (i.e. high blood pressure) referenced in the passage from the package insert is uncommon with Dexilant, occurring in less than 2% of individuals taking the drug. Nevertheless, if you do have high blood pressure, it may be prudent to check it to make sure it is still well controlled.

If you have additional concerns about any side effects you are experiencing from the extra dose of Dexilant, you should reach out to your doctor, or call the Poison Control Center at 1-800-222-1222.

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