Drug Interaction Checker
Drug Interaction Result
Checked Drugs: Ranitidine , Dicyclomine
Severity : major
Description : The therapeutic efficacy of Dicyclomine can be decreased when used in combination with Ranitidine.
Management : Avoid the use of cholinesterase inhibitors with anticholinergic agents. If use cannot be avoided, monitor the patient for reduced efficacy of the anticholinergic agent.
Full Description : Cholinesterase inhibitors increase the amount of acetylcholine available in synapses, allowing compe... Cholinesterase inhibitors increase the amount of acetylcholine available in synapses, allowing competition with anticholinergic agents for receptor binding. This can potentially reduce the therapeutic efficacy of anticholinergics when used concomitantly. Read more
Information Source : DrugBank
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