Description

Simple

Clinical

Overview

Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. It currently approved for veterinary use in dogs and horses under the brand names Equioxx and Previcox. Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses. Firocoxib is not intended or approved for use in human medicine.

Pharmacology

Indication

Used for the treatment of pain inflammation and fever in horses and dogs.

Pharmacodynamic

Information currently not available.

Mechanism of action

Information currently not available.

Absorption

Information currently not available.

Protein binding

Information currently not available.

Volume of distribution

Information currently not available.

Clearance

Information currently not available.

Half life

Information currently not available.

Route of elimination

Information currently not available.

Toxicity

Information currently not available.

Adverse Effects

Contraindications

Information currently not available.

Food Interactions

    Information currently not available.

Interactions

Type in a drug name to check for interaction with Firocoxib
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  • Paracetamol(acetaminophen)
  • Paxil(paroxetine)
  • Pamelor(nortriptyline)
  • Panadol(acetaminophen)
  • Patanol(olopatadine ophthalmic)
  • Pataday(olopatadine ophthalmic)
  • Parnate(tranylcypromine)
  • Pazeo(olopatadine ophthalmic)
(R)-warfarin
The risk or severity of bleeding and hemorrhage can be increased when Firocoxib is combined with (R)-warfarin.
(S)-Warfarin
The risk or severity of bleeding and hemorrhage can be increased when Firocoxib is combined with (S)-Warfarin.
1-benzylimidazole
The risk or severity of hypertension can be increased when 1-benzylimidazole is combined with Firocoxib.
2,5-Dimethoxy-4-ethylamphetamine
The risk or severity of hypertension can be increased when 2,5-Dimethoxy-4-ethylamphetamine is combined with Firocoxib.
2,5-Dimethoxy-4-ethylthioamphetamine
The risk or severity of hypertension can be increased when Firocoxib is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.
4-Bromo-2,5-dimethoxyamphetamine
The risk or severity of hypertension can be increased when 4-Bromo-2,5-dimethoxyamphetamine is combined with Firocoxib.
4-hydroxycoumarin
The risk or severity of bleeding and hemorrhage can be increased when Firocoxib is combined with 4-hydroxycoumarin.
4-Methoxyamphetamine
The risk or severity of hypertension can be increased when 4-Methoxyamphetamine is combined with Firocoxib.
5-methoxy-N,N-dimethyltryptamine
The risk or severity of hypertension can be increased when Firocoxib is combined with 5-methoxy-N,N-dimethyltryptamine.
Abacavir
Firocoxib may decrease the excretion rate of Abacavir which could result in a higher serum level.
Abciximab
The risk or severity of bleeding and hemorrhage can be increased when Firocoxib is combined with Abciximab.
Abediterol
The risk or severity of hypertension can be increased when Firocoxib is combined with Abediterol.
Acarbose
Firocoxib may decrease the excretion rate of Acarbose which could result in a higher serum level.
Acebutolol
Firocoxib may decrease the antihypertensive activities of Acebutolol.
Aceclofenac
The risk or severity of adverse effects can be increased when Aceclofenac is combined with Firocoxib.
Acemetacin
The risk or severity of adverse effects can be increased when Acemetacin is combined with Firocoxib.
Acenocoumarol
The risk or severity of bleeding and hemorrhage can be increased when Firocoxib is combined with Acenocoumarol.
Acepromazine
The risk or severity of hypertension can be increased when Acepromazine is combined with Firocoxib.
Acetaminophen
The risk or severity of adverse effects can be increased when Acetaminophen is combined with Firocoxib.
Acetohexamide
The protein binding of Acetohexamide can be decreased when combined with Firocoxib.