Description

Simple

Clinical

Overview

Pharmacology

Indication

Investigated for use/treatment in allergic reaction and asthma.

Pharmacodynamic

Information currently not available.

Mechanism of action

R343 is a syk kinase inhibitor. Syk kinase is a protein tyrosine kinase that plays a pivotal role in high affinity IgE receptor signaling in mast cells. Syk kinase inhibitors bind to syk in mast cells interrupting the signal from the Immunoglobulin E (IgE receptor), thus preventing cellular activa... Read more

Absorption

Information currently not available.

Protein binding

Information currently not available.

Volume of distribution

Information currently not available.

Clearance

Information currently not available.

Half life

Information currently not available.

Route of elimination

Information currently not available.

Toxicity

Information currently not available.

Adverse Effects

Contraindications

Information currently not available.

Food Interactions

    Information currently not available.

Interactions

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  • Paracetamol(acetaminophen)
  • Paxil(paroxetine)
  • Pamelor(nortriptyline)
  • Panadol(acetaminophen)
  • Patanol(olopatadine ophthalmic)
  • Pataday(olopatadine ophthalmic)
  • Parnate(tranylcypromine)
  • Pazeo(olopatadine ophthalmic)