Description

Simple

Clinical

Overview

HIF-1alpha is an inhibitor of the hypoxia–inducible factor (HIF)–1 alpha, a protein that controls the transcription of a number of genes whose products are important for tumor growth and survival.

Pharmacology

Indication

Investigated for use/treatment in lymphoma (unspecified) and solid tumors.

Pharmacodynamic

Information currently not available.

Mechanism of action

HIF-1alpha inhibits hypoxia inducible factor 1 (HIF-1), a key player in cancer progression and an attractive target for cancer therapy.

Absorption

Information currently not available.

Protein binding

Information currently not available.

Volume of distribution

Information currently not available.

Clearance

Information currently not available.

Half life

Information currently not available.

Route of elimination

Information currently not available.

Toxicity

Information currently not available.

Adverse Effects

Contraindications

Information currently not available.

Food Interactions

    Information currently not available.

Interactions

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  • Paracetamol(acetaminophen)
  • Paxil(paroxetine)
  • Pamelor(nortriptyline)
  • Panadol(acetaminophen)
  • Patanol(olopatadine ophthalmic)
  • Pataday(olopatadine ophthalmic)
  • Parnate(tranylcypromine)
  • Pazeo(olopatadine ophthalmic)