Description

Simple

An injection used to treat attacks of abdominal pain, weakness, seizures, and a fast heartbeat that happen in some women around or during menstrual cycles that are called acute intermittent porphyrias (AIP).

Clinical

An iron-containing porphyrin injection used for the relief of recurrent attacks of acute intermittent porphyria (AIP) associated with the menstrual cycle when carbohydrate therapy is not effective.

Overview

Hemin (trade name Panhematin) is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.

Pharmacology

Indication

Used in the management of porphyria attacks, particularly in acute intermittent porphyria.

Pharmacodynamic

Information currently not available.

Mechanism of action

Information currently not available.

Absorption

Information currently not available.

Protein binding

Information currently not available.

Volume of distribution

Information currently not available.

Clearance

Information currently not available.

Half life

Information currently not available.

Route of elimination

Information currently not available.

Toxicity

Information currently not available.

Adverse Effects

Contraindications

Information currently not available.

Food Interactions

    Information currently not available.

Interactions

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  • Paracetamol(acetaminophen)
  • Paxil(paroxetine)
  • Pamelor(nortriptyline)
  • Panadol(acetaminophen)
  • Patanol(olopatadine ophthalmic)
  • Pataday(olopatadine ophthalmic)
  • Parnate(tranylcypromine)
  • Pazeo(olopatadine ophthalmic)
(R)-warfarin
Hemin may increase the anticoagulant activities of (R)-warfarin.
(S)-Warfarin
Hemin may increase the anticoagulant activities of (S)-Warfarin.
4-hydroxycoumarin
Hemin may increase the anticoagulant activities of 4-hydroxycoumarin.
Abciximab
Hemin may increase the anticoagulant activities of Abciximab.
Acenocoumarol
Hemin may increase the anticoagulant activities of Acenocoumarol.
Acetylsalicylic acid
Hemin may increase the anticoagulant activities of Acetylsalicylic acid.
Alteplase
Hemin may increase the anticoagulant activities of Alteplase.
Amediplase
Hemin may increase the anticoagulant activities of Amediplase.
Anagrelide
Hemin may increase the anticoagulant activities of Anagrelide.
Ancrod
Hemin may increase the anticoagulant activities of Ancrod.
Anistreplase
Hemin may increase the anticoagulant activities of Anistreplase.
Antithrombin Alfa
Hemin may increase the anticoagulant activities of Antithrombin Alfa.
Antithrombin III human
Hemin may increase the anticoagulant activities of Antithrombin III human.
Apixaban
Hemin may increase the anticoagulant activities of Apixaban.
Ardeparin
Hemin may increase the anticoagulant activities of Ardeparin.
Argatroban
Hemin may increase the anticoagulant activities of Argatroban.
Astaxanthin
Hemin may increase the anticoagulant activities of Astaxanthin.
Bemiparin
Hemin may increase the anticoagulant activities of Bemiparin.
Beraprost
Hemin may increase the anticoagulant activities of Beraprost.
Betrixaban
Hemin may increase the anticoagulant activities of Betrixaban.