Description

Simple

A medication used to cause the eye to constrict where necessary during medical procedures.

Clinical

A parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.

Overview

A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases, but it is useful in some ophthalmological applications.

Pharmacology

Indication

Used to obtain miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.

Pharmacodynamic

Information currently not available.

Mechanism of action

Information currently not available.

Absorption

Information currently not available.

Protein binding

Information currently not available.

Volume of distribution

Information currently not available.

Clearance

Information currently not available.

Half life

Information currently not available.

Route of elimination

Information currently not available.

Toxicity

Information currently not available.

Adverse Effects

Contraindications

Information currently not available.

Food Interactions

    Information currently not available.

Interactions

Type in a drug name to check for interaction with Acetylcholine
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  • Paracetamol(acetaminophen)
  • Paxil(paroxetine)
  • Pamelor(nortriptyline)
  • Panadol(acetaminophen)
  • Patanol(olopatadine ophthalmic)
  • Pataday(olopatadine ophthalmic)
  • Parnate(tranylcypromine)
  • Pazeo(olopatadine ophthalmic)
1,10-Phenanthroline
The risk or severity of adverse effects can be increased when 1,10-Phenanthroline is combined with Acetylcholine.
Acebutolol
The risk or severity of adverse effects can be increased when Acebutolol is combined with Acetylcholine.
Acotiamide
The risk or severity of adverse effects can be increased when Acotiamide is combined with Acetylcholine.
Acyclovir
The risk or severity of adverse effects can be increased when Acyclovir is combined with Acetylcholine.
Alprenolol
The risk or severity of adverse effects can be increased when Alprenolol is combined with Acetylcholine.
Amantadine
The risk or severity of adverse effects can be increased when Amantadine is combined with Acetylcholine.
Ambenonium
The risk or severity of adverse effects can be increased when Ambenonium is combined with Acetylcholine.
Amikacin
The therapeutic efficacy of Acetylcholine can be decreased when used in combination with Amikacin.
Anisodamine
The risk or severity of adverse effects can be increased when Anisodamine is combined with Acetylcholine.
Apramycin
The therapeutic efficacy of Acetylcholine can be decreased when used in combination with Apramycin.
Aprotinin
The risk or severity of adverse effects can be increased when Aprotinin is combined with Acetylcholine.
Arbekacin
The therapeutic efficacy of Acetylcholine can be decreased when used in combination with Arbekacin.
Arotinolol
The risk or severity of adverse effects can be increased when Arotinolol is combined with Acetylcholine.
Atenolol
The risk or severity of adverse effects can be increased when Atenolol is combined with Acetylcholine.
Bambuterol
The risk or severity of adverse effects can be increased when Bambuterol is combined with Acetylcholine.
Befunolol
The risk or severity of adverse effects can be increased when Befunolol is combined with Acetylcholine.
Bekanamycin
The therapeutic efficacy of Acetylcholine can be decreased when used in combination with Bekanamycin.
Betaxolol
The risk or severity of adverse effects can be increased when Betaxolol is combined with Acetylcholine.
Bevantolol
The risk or severity of adverse effects can be increased when Bevantolol is combined with Acetylcholine.
Bisoprolol
The risk or severity of adverse effects can be increased when Bisoprolol is combined with Acetylcholine.