Description

Simple

Clinical

Overview

A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed)

Pharmacology

Indication

Information currently not available.

Pharmacodynamic

Information currently not available.

Mechanism of action

Information currently not available.

Absorption

Information currently not available.

Protein binding

Information currently not available.

Volume of distribution

Information currently not available.

Clearance

Information currently not available.

Half life

Information currently not available.

Route of elimination

Information currently not available.

Toxicity

Information currently not available.

Adverse Effects

Contraindications

Information currently not available.

Food Interactions

    Information currently not available.

Interactions

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  • Paracetamol(acetaminophen)
  • Paxil(paroxetine)
  • Pamelor(nortriptyline)
  • Panadol(acetaminophen)
  • Patanol(olopatadine ophthalmic)
  • Pataday(olopatadine ophthalmic)
  • Parnate(tranylcypromine)
  • Pazeo(olopatadine ophthalmic)
(R)-warfarin
The metabolism of (R)-warfarin can be decreased when combined with Xanthine.
2,5-Dimethoxy-4-ethylamphetamine
The risk or severity of adverse effects can be increased when 2,5-Dimethoxy-4-ethylamphetamine is combined with Xanthine.
2,5-Dimethoxy-4-ethylthioamphetamine
The risk or severity of adverse effects can be increased when 2,5-Dimethoxy-4-ethylthioamphetamine is combined with Xanthine.
3,5-Diiodotyrosine
3,5-Diiodotyrosine may decrease the excretion rate of Xanthine which could result in a higher serum level.
4-Bromo-2,5-dimethoxyamphetamine
The risk or severity of adverse effects can be increased when 4-Bromo-2,5-dimethoxyamphetamine is combined with Xanthine.
6-Deoxyerythronolide B
The metabolism of Xanthine can be decreased when combined with 6-Deoxyerythronolide B.
6-O-benzylguanine
The metabolism of 6-O-benzylguanine can be decreased when combined with Xanthine.
7-Nitroindazole
7-Nitroindazole may increase the excretion rate of Xanthine which could result in a lower serum level and potentially a reduction in efficacy.
8-azaguanine
The metabolism of Xanthine can be decreased when combined with 8-azaguanine.
8-chlorotheophylline
The metabolism of 8-chlorotheophylline can be decreased when combined with Xanthine.
9-Deazaguanine
The metabolism of 9-Deazaguanine can be decreased when combined with Xanthine.
9-Methylguanine
The metabolism of 9-Methylguanine can be decreased when combined with Xanthine.
Abatacept
The metabolism of Xanthine can be increased when combined with Abatacept.
Abiraterone
The serum concentration of Xanthine can be increased when it is combined with Abiraterone.
Acebutolol
The risk or severity of adverse effects can be increased when Acebutolol is combined with Xanthine.
Acefylline
The metabolism of Acefylline can be decreased when combined with Xanthine.
Acenocoumarol
The metabolism of Xanthine can be decreased when combined with Acenocoumarol.
Acetaminophen
The metabolism of Xanthine can be decreased when combined with Acetaminophen.
Acetazolamide
Acetazolamide may increase the excretion rate of Xanthine which could result in a lower serum level and potentially a reduction in efficacy.
Acyclovir
The metabolism of Xanthine can be decreased when combined with Acyclovir.