Description

Simple

A medication used to treat ulcers.

Clinical

A muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers.

Overview

Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.

Pharmacology

Indication

Used in conjunction with antacids or histamine H2-receptor antagonists in the treatment of peptic ulcers, gastric ulcers and duodenal ulcers, to reduce further gastric acid secretion and delay gastric emptying.

Pharmacodynamic

Homatropine methylbromide belongs to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomitin... Read more

Mechanism of action

Homatropine is a quaternary ammonium muscarinic acetylcholine receptor antagonist. The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G protein... Read more

Absorption

Information currently not available.

Protein binding

Information currently not available.

Volume of distribution

Information currently not available.

Clearance

Information currently not available.

Half life

Information currently not available.

Route of elimination

Information currently not available.

Toxicity

Information currently not available.

Adverse Effects

Contraindications

Information currently not available.

Food Interactions

    Information currently not available.

Interactions

Type in a drug name to check for interaction with Homatropine methylbromide
Type a drug name in the box above to get started
  • Paracetamol(acetaminophen)
  • Paxil(paroxetine)
  • Pamelor(nortriptyline)
  • Panadol(acetaminophen)
  • Patanol(olopatadine ophthalmic)
  • Pataday(olopatadine ophthalmic)
  • Parnate(tranylcypromine)
  • Pazeo(olopatadine ophthalmic)
1,10-Phenanthroline
The therapeutic efficacy of Homatropine methylbromide can be decreased when used in combination with 1,10-Phenanthroline.
2,5-Dimethoxy-4-ethylamphetamine
The risk or severity of Tachycardia can be increased when Homatropine methylbromide is combined with 2,5-Dimethoxy-4-ethylamphetamine.
2,5-Dimethoxy-4-ethylthioamphetamine
2,5-Dimethoxy-4-ethylthioamphetamine may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
4-Bromo-2,5-dimethoxyamphetamine
4-Bromo-2,5-dimethoxyamphetamine may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
4-Methoxyamphetamine
4-Methoxyamphetamine may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
5-methoxy-N,N-dimethyltryptamine
5-methoxy-N,N-dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
7-Nitroindazole
7-Nitroindazole may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
Abediterol
The risk or severity of Tachycardia can be increased when Homatropine methylbromide is combined with Abediterol.
Acepromazine
Acepromazine may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
Aceprometazine
Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
Acetazolamide
Acetazolamide may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
Acetophenazine
Acetophenazine may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
Acetylglycinamide chloral hydrate
Acetylglycinamide chloral hydrate may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
Aclidinium
The risk or severity of adverse effects can be increased when Homatropine methylbromide is combined with Aclidinium.
Acotiamide
The therapeutic efficacy of Homatropine methylbromide can be decreased when used in combination with Acotiamide.
Adenosine
The risk or severity of Tachycardia can be increased when Adenosine is combined with Homatropine methylbromide.
Adinazolam
Adinazolam may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
Adipiplon
Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
Adrafinil
The risk or severity of Tachycardia can be increased when Homatropine methylbromide is combined with Adrafinil.